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  1. JACS
    UNUSUAL REARRANGEMENT OF AN
    N-DONOR-FUNCTIONALIZED N-HETEROCYCLIC
    CARBENE LIGAND ON GROUP 8 METALS
    The Song group discovered an unusual rearrangement reaction,where
    the N,C-chelate ligand of a piano-stool Group 8complex isomerizes into
    an N,N-chelate ligand. Mechanistic study suggests the involvement of a
    high-energy metal-alkylidene intermediate.
    Song group, Journal of the American Chemical Society, 2018
  2. Cell
    DYSREGULATION OF MITOCHONDRIAL CLPP
    PROTEASE AS A POTENTIAL STRATEGY TO
    DEVELOP NOVEL ANTICANCERS
    Human mitochondrial ClpP was found to be activated by specific
    acyldepsipeptide compounds causing apoptotic cell death.
    Houry and Batey groups, Cell Chemical Biology, 2018
  3. Nature
    AMINE HEMILABILITY ENABLES BORON TO
    MECHANISTICALLY RESEMBLE EITHER
    HYDRIDE OR PROTON
    Mechanistic studies of the hemilability of MIDA
    (N-methyliminodiacetic acid) boronates reveal the chameleonic
    behaviour of the BMIDA group.
    Yudin group, Nature Chemistry, 2018
  4. Nature
    TIPPING CELL SIGNALING PATHWAYS BY SALTS
    Mechanistic insights into allosteric regulation ofthe A2A adenosine
    G protein-coupled receptor byphysiological cations.
    Prosser group, Nature Communications, 2018
  5. Journal of the American Chemical Society
    COMPETITIVE SELF-ASSEMBLY KINETICS AS A
    ROUTE TO CONTROLLING MORPHOLOGY OF
    CORE-CRYSTALLINE CYLINDRICAL MICELLESS
    One can manipulate the seeded-growth kinetics of block
    copolymer unimers to control the growth sequence of
    unimers and thus the comicelle morphology.
    Winnik group, Journal of the American Chemical Society, 2018
  6. Oncogene
    INHIBITING MYC BINDING TO THE E-BOX DNA
    MOTIF BY ME47 DECREASES
    TUMOUR XENOGRAFT GROWTH
    The Shin lab's designed protein ME47 decreased tumor growth in
    a triple negative breast cancer mouse model, a type of cancer with
    no effective treatments.
    Shin, Chan & Penn groups, Oncogene, 2017

Awards:

Chemistry professors among the most cited

Chemistry professors among the most cited

Congratulations to Professors Doug Stephan, Warren Chan and Oleksandr Voznyy for being named 2018 Highly Cited Researchers by Clarivate Analytics.

They are being recognized for their exceptional research performance, demonstrated by the production of multiple highly cited papers that rank in the top 1% by citations in their field.


News and Announcements:

Professor Derek Muir wins lifetime award for northern research

Professor Derek Muir wins lifetime award for northern research

Professor Derek Muir is the recipient of the $100,000 Weston Family prize for northern research by The W. Garfield Weston Foundation.

Professor Muir is being recognized for a lifetime of research, including his work on contaminants in the Arctic environment that helped lead to global controls on toxic chemicals.



Professor Andy Dicks promoted to Professor

Professor Andy Dicks promoted to Professor

Congratulations to Professor Andy Dicks, who has been promoted to Professor, Teaching Stream. Professor Dicks becomes one of the first faculty members to be promoted to this position within the Faculty of Arts and Science.






Professor Alán Aspuru-Guzik: Teaching chemistry students to use the labs of the future

Professor Alán Aspuru-Guzik: Teaching chemistry students to use the labs of the future

Professor Alán Aspuru-Guzik is featured in Chemical & Engineering News where he talks about the importance of data science and machine learning in chemistry education.

"We are not going to succeed at automated chemistry if we do not have automation education," he says.



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