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  1. Nature
    AMINE HEMILABILITY ENABLES BORON TO
    MECHANISTICALLY RESEMBLE EITHER
    HYDRIDE OR PROTON
    Mechanistic studies of the hemilability of MIDA
    (N-methyliminodiacetic acid) boronates reveal the chameleonic
    behaviour of the BMIDA group.
    Yudin group, Nature Chemistry, 2018
  2. Nature
    TIPPING CELL SIGNALING PATHWAYS BY SALTS
    Mechanistic insights into allosteric regulation ofthe A2A adenosine
    G protein-coupled receptor byphysiological cations.
    Prosser group, Nature Communications, 2018
  3. Journal of the American Chemical Society
    COMPETITIVE SELF-ASSEMBLY KINETICS AS A
    ROUTE TO CONTROLLING MORPHOLOGY OF
    CORE-CRYSTALLINE CYLINDRICAL MICELLESS
    One can manipulate the seeded-growth kinetics of block
    copolymer unimers to control the growth sequence of
    unimers and thus the comicelle morphology.
    Winnik group, Journal of the American Chemical Society, 2018
  4. Oncogene
    INHIBITING MYC BINDING TO THE E-BOX DNA
    MOTIF BY ME47 DECREASES
    TUMOUR XENOGRAFT GROWTH
    The Shin lab's designed protein ME47 decreased tumor growth in
    a triple negative breast cancer mouse model, a type of cancer with
    no effective treatments.
    Shin, Chan & Penn groups, Oncogene, 2017
  5. DNA
    PROTEIN DIMERIZATION PARTNERS ARE DICTATED
    BY THE DNA TARGET, NOT PROTEIN TARGET
    Many genes are regulated by protein hetero- or homodimers. Shin et
    al found that DNA bases outside the protein-DNA recognition target
    determine the protein dimerization partner.
    Shin Group, Molecular Biosystems, January 2017
  6. THE ROLE OF DIMER ASYMMETRY AND
    PROTOMER DYNAMICS IN ENZYME CATALYSIS
    Prosser and coauthor Pai examine a homodimeric enzyme, fluoroacetate
    dehalogenase, which converts a highly toxic pesticide into a harmless
    metabolite, and explore the role of enzyme dynamics in the process.
    Prosser Group, Science, January 2017

Awards:

Professor Dwight Seferos wins McLean Award for his work developing eco-friendly batteries

Professor Dwight Seferos wins McLean Award for his work developing eco-friendly batteries

Professor Dwight Seferos is this year’s recipient of the $125,000 McLean Award, which he will use to delve deeper into developing new biodegradable polymers or plastics that can store energy from solar, wind and tidal power.

The award is designed to support the basic research of an outstanding early career researcher in physics, chemistry, computer science, mathematics, engineering sciences, or the theory and methods of statistics.


News and Announcements:

Professor Dwight Seferos receives NSERC grant to create new flexible electronics

Professor Dwight Seferos receives NSERC grant to create new flexible electronics

Professor Dwight Seferos is one of 12 U of T scientists and engineers to receive a 2018 Strategic Partnership Grant from the Natural Sciences and Engineering Research Council of Canada (NSERC).

These grants are awarded to researchers who are working alongside policy makers and Canadian companies to transfer knowledge and generate new technology.


Professor Andrei Yudin's exploration of 'chameleon' MIDA boronates featured in Chemistry World

Professor Andrei Yudin's exploration of 'chameleon' MIDA boronates featured in Chemistry World

In a recent paper in Nature Chemistry, Professor Andrei Yudin describes the migratory ability of the MIDA boryl group in boron transfer processes, and showed that the hemilability of the nitrogen atom on the MIDA ligand enables boron to mechanistically resemble either a hydride or a proton. His work is featured on Chemistry World.




U of T researchers conduct most comprehensive airborne mercury testing in GTA

U of T researchers conduct most comprehensive airborne mercury testing in GTA

University of Toronto researchers, including Professor Frank Wania of the department of chemistry, say they have conducted the most comprehensive monitoring of airborne mercury ever in the GTA, finding that although mercury concentrations continue to be low, emission levels officially reported to the government are often inaccurate.

 

 


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