Patrick Gunning Wins 2016 CSC Bernard Belleau Award
Congratulations to Prof. Patrick Gunning has been named the 2016 recipient of the CSC Bernard Belleau Award. The Bernard Belleau Award is presented to a scientist residing in Canada who has made a distinguished contribution to the field of medicinal chemistry through research involving biochemical or organic chemical mechanisms.
“Resetting the Doomsday Clock” – Editorial by John Polanyi Published in The Globe and Mail
This week, the Bulletin of Atomic Scientists, the “conscience of scientists,” met in Chicago to reset its Doomsday Clock and set the hands at three minutes to midnight. In an editorial published by The Globe and Mail, Prof. John Polanyi discusses the existential threats of climate change and nuclear war recognized by The Bulletin, and of the responsibility of scientists to alert of these dangers.
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Optimizing photo-control of bZIP coiled-coils by azobenzene
The cover picture shows a photoswitchable azobenzene cross-linked peptide (red) that acts as a dominant negative inhibitor of DNA binding by the transcription factor CREB (green). The DNA target is shown in white. G. A. Woolley and co-workers show that the largest degree of conformational control is obtained when the photoswitchable cross-linker is placed at the site of highest intrinsic helical propensity in the inhibitor.
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