Content: The course surveys principles and mechanisms of organic reactions. Systematic approaches are emphasized along with connections to physical models. The laboratory is designed to provide experience with the use of the essential concepts and methods. The course begins by examining principles of structure and reactivity. Reactive intermediates and reaction pathways are examined in terms of molecular classes and reaction types. The emphasis is on material that can serve as a basis for the study of reaction mechanisms and reactivity in contexts that include: synthesis, biochemistry, environment, and materials.
Texts: The required text is F. A. Carey and R. J. Sundberg "Advanced Organic Chemistry" PART A - Structure and Mechanism, 5th edition (2007). It contains most of the reading material and problems. For those who want more books to read there is fine material on several topics in Peter Sykes "A Guidebook to Mechanism in Organic Chemistry", 6th edition. For those who would like to see the same material at a higher level, we recommend Lowry and Richardson's "Mechanism and Theory in Organic Chemistry." The large new book by Anslyn and Dougherty, "Modern Physical Organic Chemistry" covers all the topics and offers many interesting examples. Any additional required reading will be posted on this web site.
Lectures: T and R 2
Lecturer: Professor Ronald Kluger
Laboratory Instructor: Dr. Stan Skonieczny
Phone: 416-978-3582. Office: Davenport 444. Office Hours MWF 11-12. Please confirm your visit in advance. Email: Only email from utoronto.ca accounts will be accepted. The email should first include your name and student number and identify that you are in CHM 348. Please limit content to requests for appointments or schedule issues. Questions about chemistry need to be discussed in person in order to be clear. Click on the mailbox to send an email.
Laboratory: This is designed and supervised by Dr. Stan Skonieczny. For contact information and more information about the lab please click here.
If you do not write a test your grade on that test is 0. If you have a completed satisfactory medical note on the approved form submitted to one of the instructors, your final grade will be based on whatever term work has been graded.
Note: All requests for re-marking must be submitted in writing within one week of the date the test is returned to the class.
Grading: Final examination (50 %), term tests (25 %) Laboratory, including reports (25%). Problems will be suggested but not graded. We do not supply previous tests.
Lecture and examination schedule
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