Course content:  

An in depth examination of biological systems at the molecular level. Several complex, multi-subunit molecular machines with a central role in life will be discussed. For each system studied, the focus will be on understanding the chemical mechanisms that underlie their biological activities and how these processes fit into a cellular context. This year, the course will cover transcription, translation, glycosylation and examples of proteins with specialized functions in the cell.

Prerequisites:

CHM 447H and BCH 210/242Y

Suggested Text:  

"Biochemistry" by D. Voet & J. G. Voet, 3rd Edition, Wiley 2004.
Journal articles will also be assigned and can be accessed through blackboard

Lectures:

Tuesdays and Thursdays, 11:00 - 12:00 pm in LM158

Office Hours:  

After class or email for an appointment

Instructors

Mark Nitz                                                   
Email:  mnitz@chem.utoronto.ca                                     
Phone:  416-946-0640                                                         
Office:  LM 462

Deborah Zamble                                                   
Email:  dzamble@chem.utoronto.ca                                     
Phone:  416-978-3568                                                         
Office:  LM 443

Drew Woolley (Course coordinator)                                                   
Email:  awoolley@chem.utoronto.ca                                     
Phone:  416-978-0675                                                        
Office:  LM 526