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Hui Peng

Hui Peng

Academic Title: Assistant Professor

Phone: 416-978-4756

Office: LM 512

Email:

Research

Research in our group relies on the interface between chemistry and biology to answer fundamental environmental questions. We focus on the development of novel techniques to address the following bottlenecks of current environmental science research: i) the limited capacity of traditional targeted chemical analysis strategies to monitor the growing number of known and unknown environmental chemicals introduced into commerce ; ii) limited information is available regarding toxic mechanisms (i.e., protein targets) for the vast majority of environmental chemicals. We are currently focusing on three research directions:

  • Untargeted identification of novel environmental chemicals
  • Investigation on sources and behaviors of environmental chemicals
  • Unbiased identification of protein targets by chemical proteomics

Selected Publications

  1. Peng H, Guo HB, Pogoutse O, Wan CH, Hu ZL, Ni ZY, Emili A. (2016) An unbiased chemical proteomics method identifies FabI as the primary protein target of 6-OH-BDE-47. Environ. Sci. Technol. 50, 11329-11336.
  2. Peng H, Saunders DMV, Sun JX, Johns PD, Wong CKS, Liu HL, Giesy JP. (2016) Mutagenic Azo dyes, rather than flame retardants, are predominant brominated compounds in house dust. Environ. Sci. Technol. 50, 12669-12677 (Featured in C&EN).
  3. Peng H, Sun JX, Alharbi HA, Jones PD, Giesy JP, Wiseman S. (2016) Peroxisome proliferator-activated receptor ? is a sensitive target for oil sands process-affected water: effects on adipogenesis and identification of ligands. Environ. Sci. Technol. 50, 7816-7824.
  4. Peng H, Chen CL, Cantin J, Saunders DMV, Sun JX, Tang S, Codling G, Hecker M, Wiseman S, Johns PD, Li A, Rockne K, Sturchio NC, Giesy JP. (2016) Untargeted screening and distribution of organo-bromine compounds in sediments of Lake Michigan. Environ. Sci. Technol. 50, 321-330.
  5. Sun JX, Tang S, Peng H*, Saunders DMV, Doering JA, Hecker M, Jones PD, Giesy JP, Wiseman S. (2016) A combined transcriptomic and proteomic approach to identify and predict toxicity pathways in early-life stages of Japanese medaka (Oryzias latipes) exposed to 1,2,5,6-tetrabromocyclooctane (TBCO). Environ. Sci. Technol.50, 7781-7790.
  6. Peng H, Chen CL, Cantin J, Saunders DMV, Sun JX, Tang S, Codling G, Hecker M, Wiseman S, Johns PD, Li A, Rockne K, Sturchio NC, Giesy JP. (2016) Untargeted screening and distribution of organo-iodine compounds in sediments of Lake Michigan. Environ. Sci. Technol. 50, 1009710105.
  7. Peng H, Saunders DMV, Sun JX, Codling G, Wiseman S, Johns PD, Giesy JP. (2015) Detection, identification, and quantification of hydroxylated bis (2-ethylhexyl)-tetrabromophthalate isomers in house dust. Environ. Sci. Technol. 49,2999-3006.
  8. Peng H, Chen CL, Cantin J, Saunders DMV, Sun JX, Tang S, Codling G, Hecker M, Wiseman S, Johns PD, Li A, Rockne K, Sturchio NC, Giesy JP. (2015) Untargeted identification of organo-bromine compounds in lake sediments by ultrahigh-resolution mass spectrometry with the data-independent precursor isolation and characteristic fragment method. Anal. Chem.87, 10237-10246.
  9. Peng H, Wan Y, Zhang K, Sun JX, Hu JY. (2014) Trophic transfer of dechloranes in the marine food web of Liaodong Bay, North China. Environ. Sci. Technol. 48,5458-5466.
  10. Peng H, Zhang SY, Sun JX, Zhang Z, Giesy JP, Hu JY. (2014) Isomer-specific accumulation of perfluorooctanesulfonate from (N-Ethyl prefluorooctanesulfonamido) ethanol-basesd phosphate diester in Japanese Medaka (Oryzias latipes). Environ. Sci. Technol. 48, 1058-1066.
  11. Hu JY, Zhang ZB, Wei QW, Zhen HJ, Zhao YB, Peng H, Wan Y, Giesy JP, Li LX, and Zhang B. (2009) Malformations of the endangered Chinese sturgeon, Acipenser sinensis, and its causal agent. Proc. Natl. Acad. Sci. 106, 9339-9344.