The Jockusch Lab


J. TiefenbachL. MagomedovaJ. LiuA. A. ReunovR. TsaiN. S. EappenR. A. JockuschC. NislowC. L. CumminsH. M. Krause, “Idebenone and coenzyme Q10 are novel PPARα/γ ligands, with potential for treatment of fatty liver diseases,” Disease Models & Mechanisms, (2018). DOI: 10.1242/dmm.034801.

Back Cover
S.M.J. Wellman, R.A. Jockusch, “Tuning the intrinsic photophysical properties of chlorophyll a,” Chemistry: A European Journal, 23(32), 7728-7736 (2016). DOI: 10.1002/chem.201605167. (Back Cover)


R.N. Straus, R.A. Jockusch, “Probing the gaseous structure of a β-hairpin peptide with H/D exchange and electron capture dissociation,” Journal of the American Society for Mass Spectrometry, 28, 358-369 (2016). DOI: 10.1007/s13361-016-1528-4.

M.F. Czar, R.A. Jockusch, “Sensitive probes of protein structure and dynamics in well-controlled environments: combining mass spectrometry with fluorescence spectroscopy,” Current Opinion in Structural Biology, 34, 123–134 (2015). DOI: 10.1016/

S.V. Sciuto, R.A. Jockusch, “The intrinsic photophysics of gaseous ethidium ions,” Journal of Photochemistry and Photobiology, A: Chemistry, 311, 186–192 (2015).  DOI: 10.1016/j.jphotochem.2015.06.020.

M.F. Czar, R.A. Jockusch, “Gas-phase FRET Efficiency Measurements to Probe the Conformation of Mass-Selected Proteins,” Analytical Chemistry, 87(15) 7559–7565 (2015). ACS Editors’ Choice article. DOI: 10.1021/acs.analchem.5b01591.

S.M.J. Wellman, R.A. Jockusch, “Moving in on the Action: An Experimental Comparison of Fluorescence Excitation and Photodissociation Action Spectroscopy,” The Journal of Physical Chemistry A, 119(24), 6333–6338 (2015). DOI: 10.1021/acs.jpca.5b04835.

F.O. Talbot, S.V. Sciuto, and R.A. Jockusch, “Fluorescence imaging for visualization of the ion cloud in a quadrupole ion trap mass spectrometer”, Journal of The American Society for Mass Spectrometry, 24(12),1823-1832 (2013). DOI: 10.1007/s13361-013-0742-6.

M.F. Czar and R.A. Jockusch, “Understanding Photophysical Effects of Cucurbituril Encapsulation: A Model Study with Acridine Orange in the Gas Phase”, ChemPhysChem, 14(6), 1138-1148 (2013). Designated as Very Important Paper (Inside Cover). DOI: 10.1002/cphc.201201008.


H. Yao and R.A. Jockusch, “Fluorescence and electronic action spectroscopy of mass-selected gas-phase fluorescein, 2′,7′-dichlorofluorescein, and 2′,7′-difluorofluorescein ions”, Journal of Physical Chemistry A, 117(6), 1351-1359 (2013). DOI: 10.1021/jp309767f.

B.L. Heath and R.A. Jockusch, “Ligand Migration in the Gaseous Insulin-CB7 Complex-A Cautionary Tale About the Use of ECD-MS for Ligand Binding Site Determination”, Journal of The American Society for Mass Spectrometry, 23(11), 1911-1920 (2012). DOI: 10.1007/s13361-012-0470-3.

A.M. Nagy, F.O. Talbot, M.F. Czar, and R.A. Jockusch, “Fluorescence Lifetimes of Rhodamine Dyes in Vacuo“, Journal of Photochemistry and Photobiology A, 244, 47-53 (2012). DOI: 10.1016/j.jphotochem.2012.06.017.

J. Pan, B.L. Heath, R.A. Jockusch, and L. Konermann, “Structural Interrogation of Electrosprayed Peptide Ions by Gas-Phase H/D Exchange and Electron Capture Dissociation Mass Spectrometry”, Analytical chemistry, 84(1), 373-378 (2011). DOI: 10.1021/ac202730d.

H. Yao, J.D. Steill, J. Oomens, and R.A. Jockusch, “Infrared Multiple Photon Dissociation Action Spectroscopy and Computational Studies of Mass-Selected Gas-Phase Fluorescein and 2′,7′-Dichlorofluorescein Ions”, J. Phys. Chem. A, 115(34), 9739-9747 (2011). DOI: 10.1021/jp201946a.

M.W. Forbes, A.M. Nagy, and R.A. Jockusch, “Photofragmentation of and electron photodetachment from a GFP model chromophore in a quadrupole ion trap”, International Journal of Mass Spectrometry, 308(2-3), 155-166 (2011). DOI: 10.1016/j.ijms.2011.08.016.

S.K. Sagoo and R.A. Jockusch, “The fluorescence properties of cationic rhodamine B in the gas phase”, Journal of Photochemistry and Photobiology A: Chemistry, 220(2-3), 173-178 (2011). DOI: 16/j.jphotochem.2011.04.008.

M.W. Forbes and R.A. Jockusch, “Gas-Phase Fluorescence Excitation and Emission Spectroscopy of Three Xanthene Dyes (Rhodamine 575, Rhodamine 590 and Rhodamine 6G) in a Quadrupole Ion Trap Mass Spectrometer”,Journal of The American Society for Mass Spectrometry, 22(1), 93-109 (2011). DOI: 10.1007/s13361-010-0017-4.

V.A. Braz, M.D. Barkley, R.A. Jockusch, and P.L. Wintrode, “Efavirenz Binding Site in HIV-1 Reverse Transcriptase Monomers”, Biochemistry, 49(49), 10565-10573 (2010). DOI: 10.1021/bi101480z..

F.O. Talbot, A. Rullo, H. Yao, and R.A. Jockusch, “Fluorescence Resonance Energy Transfer in Gaseous, Mass-Selected Polyproline Peptides”, Journal of the American Chemical Society, 132(45), 16156-16164 (2010). DOI:10.1021/ja1067405.

P.D. McQueen, S. Sagoo, H. Yao, and R.A. Jockusch, “On the Intrinsic Photophysics of Fluorescein”, Angewandte Chemie International Edition, 49(48), 9193-9196 (2010). DOI: 10.1002/anie.201004366.

Q. Bian, M.W. Forbes, F.O. Talbot, and R.A. Jockusch, “Gas-phase fluorescence excitation and emission spectroscopy of mass-selected trapped molecular ions”, Physical Chemistry Chemical Physics, 12(11), 2590-2598 (2010). DOI: 10.1039/b921076h.

M.W. Forbes and R.A. Jockusch, “Deactivation Pathways of an Isolated Green Fluorescent Protein Model Chromophore Studied by Electronic Action Spectroscopy”, Journal of the American Chemical Society, 131(47), 17038-17039 (2009). DOI: 10.1021/ja9066404.

M.W. Forbes, F.O. Talbot, and R.A. Jockusch, “The Spectroscopy of Ions Stored in Trapping Mass Spectrometers” in Practical Aspects of Trapped Ion Mass Spectrometry: Applications of Ion Trapping Devices 5, 239-290 (2009).

M.W. Forbes, M.F. Bush, N.C. Polfer, J. Oomens, R.C. Dunbar, E.R. Williams, and R.A. Jockusch, “Infrared spectroscopy of arginine cation complexes: Direct observation of gas-phase zwitterions”, Journal of Physical Chemistry A, 111(46), 11759-11770 (2007). DOI: 10.1021/jp074859f.

M.F. Bush, M.W. Forbes, R.A. Jockusch, J. Oomens, N.C. Polfer, R.J. Saykally, and E.R. Williams, “Infrared spectroscopy of cationized lysine and epsilon-N-methyllysine in the gas phase: Effects of alkali-metal ion size and proton affinity on zwitterion stability”, Journal of Physical Chemistry A, 111(32), 7753-7760 (2007). DOI: 10.1021/jp071902q.