Sherif Kaldas was born and raised in Toronto, Ontario. He completed his B.Sc. Hons. in Biopharmaceutical Science Medicinal Chemistry at the University of Ottawa. He first began undergraduate research under the guidance of Dr. Tony Durst. He then completed his honour’s thesis under the supervision of Dr. Louis Barriault, where he worked on the development of gold catalyzed photoredox reactions. Sherif joined the Yudin Group in May of 2014 where he began his graduate studies, with interests in organic methodology.
Joanne Tan was born in Stoney Creek, Ontario. She received her B. Sc. in Honours Chemical Biology at McMaster University. As an undergraduate student, she explored the fields of germene chemistry, peptide macrocyclizations and radiochemistry. In 2014, she joined Prof. Yudin’s group as a graduate student and is focusing her interests in the synthesis and application of borylated compounds.
Diego Diaz received his Honours Bachelor of Science degree in biological chemistry from the University of Toronto in 2014, completing his fourth year thesis in medicinal chemistry under the supervision of Dr. Patrick Gunning. Diego then joined the Yudin group as a summer student researcher and is pursuing his interests in synthesis and methodology as a graduate student. Outside of lab, Diego enjoys spending time with friends and family, and playing all sort of team sports, especially soccer.
Aleksandra Holownia is a Toronto native. She received her Honours Bachelor of Science degree in chemistry and biochemistry from the University of Toronto in 2015. Aleksandra joined the Yudin group in the summer of 2014, and has since participated in a variety of research projects. Her interests include the synthesis of boron based building blocks and their application towards value-added products.
Harry Soor was born and raised in the city of Brampton, Ontario. Harry completed his H.B.Sc at the University of Toronto Mississauga with a double major in Chemistry and Biology. He completed his honour’s thesis under the supervision of Dr. Patrick Gunning, where he worked on the development of selective chemosensor technologies for detecting phosphorylated proteins. Harry then joined the Yudin group in September 2015, with interests in both organic synthesis and chemical probe design.
Solomon Appavoo was born in Sioux Lookout, Ontario. He received his Honours B.Sc. in Chemistry from Carleton University and completed his thesis work on the development of selective SLK inhibitors under the supervision of Dr. Jeffrey Manthorpe. In May 2016, Solomon joined the Yudin group as a PhD student with interests in synthesis and conformational analysis of biologically relevant complex molecules.
Sean Huh was born in Changwon, South Korea and raised in Edmonton, Alberta. He then moved to Vancouver, BC where he completed his BSc at the University of British Columbia with a major in chemistry. He was introduced to research by Dr. Chris Orvig where he worked on the synthesis of Ga-68 chelators for PET imaging of myocardial infarction. Next, under the supervision of Dr. David M. Perrin, he worked on the synthesis and conjugation of the organotrifluoroborate moiety into peptides and other biomolecules for F-18 PET imaging. In September 2017, Sean joined the Yudin lab as a graduate student with interests in macrocycle synthesis.
Chirag Apte was born and raised in Mumbai, India and moved to Vancouver, BC in 2012 to pursue his undergraduate degree in Chemistry at the University of British Columbia. He began his first stint in research with Dr. Marco Ciufolini and later completed his Honours thesis in the Ciufolini group working on hypervalent iodine catalysis. He has also worked on radical methodology (Dr. Glenn Sammis), chelator synthesis (Dr. Chris Orvig) and metal quantification (Bayer-Schering). Chirag joined the Yudin group in September 2017 to explore the chemistry and synthesis of boron-containing heterocycles.
Chieh Hung Tien was born and raised in Kaohsiung, Taiwan. He received both his B.Sc. Hons. and M.Sc. in Chemistry from Dalhousie University, where he worked under the supervision of Dr. Alexander Speed. Tien worked on the synthesis of organomagnesium reagents, and heterocyclic main group catalysts during the course of his studies. In May 2018, Tien joined the Yudin group as a summer research student with interests in the synthetic utility of boron-containing building blocks.
Vincent Trudel was born and raised in Montreal, Quebec. He received his B.Sc. Honours in Bio-Organic Chemistry at McGill University in 2018, where he completed his undergraduate honour’s thesis under the supervision of Prof. Youla Tsantrizos. His research focused on the synthesis of thiazolopyrimidine-based bisphosphonates as hGGPPS inhibitors. Vincent joined the Yudin Group in September 2018, with interests in reaction discovery and synthetic methodology.
Christiaan van Campenhout was born and raised in Amsterdam, The Netherlands. He completed his bachelors in chemistry at the University of Amsterdam after working in the lab of Dr. M.A. Fernández Ibáñez and Prof. Dr. J.H. van Maarseveen. Here he worked on a project in which he successfully applied a C-H activation method to cyclize peptides. Currently he is working towards a master’s degree in Molecular Science, also at the University of Amsterdam. Christiaan joined the Yudin group in September 2018 as a visiting student to get more experience with peptide-based macrocycles.
Shinya Kobori was born and raised in Shiga, Japan. He received his M.Sc. at Kyoto University, where he worked on the project about the synthesis and evaluation of the role of the mitochondrial-specific lipid, cardiolipin. In 2011, he joined Nippon-Soda Co. Ltd., where he has worked on the development of new agrochemicals. Shinya joined the Yudin Group in November 2018, with interests in synthesis of macrocycles and reaction methodology.
Postdoctoral Fellows and Research Associates:
Akitake Yamaguchi was born and raised in Chiba, Japan. Akitake’s Ph.D. work on the development of catalytic asymmetric reactions was carried out under the supervision of Prof. Shibasaki at the University of Tokyo. In 2010, Akitake joined Daiichi Sankyo Co. Ltd. as a medicinal chemist and worked on several drug discovery projects. Akitake joined Prof. Yudin’s group in October 2017 with interests in the synthesis and analysis of macrocyclic molecules.
Yury Lebedev was born in Furmanov and received his diploma in Chemistry in 2008 at the Ivanovo State University of Chemistry and Technology in Russia. He obtained his PhD degree in the research group of Professor Alexander C. Filippou at the University of Bonn (Germany), where he was exploring the chemistry of silicon and germanium analogues of metal-carbyne complexes. In 2014 he started his postdoctoral appointment in the research group on Professor Magnus Rueping working on asymmetric homogeneous organo- and transition metal catalysis projects at the RWTH Aachen University (Germany) and later in 2016 at the King Abdullah University in Saudi Arabia. Yury joined the Yudin group in June 2018 and is working on the development of novel boron-containing reagents.
Joshua Graham was born in Guelph, Ontario in 1996. He is going into his fourth year at the University of Toronto in a Chemistry and Biochemistry Double Major. He is currently working as an NSERC Undergraduate Research Award recipient under the supervision of Sherif Kaldas in the synthesis of β-amino boronate peptidomimetics.