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  1. Nature
    TIPPING CELL SIGNALING PATHWAYS BY SALTS
    Mechanistic insights into allosteric regulation ofthe A2A adenosine
    G protein-coupled receptor byphysiological cations.
    Prosser group, Nature Communications, 2018
  2. Journal of the American Chemical Society
    COMPETITIVE SELF-ASSEMBLY KINETICS AS A
    ROUTE TO CONTROLLING MORPHOLOGY OF
    CORE-CRYSTALLINE CYLINDRICAL MICELLESS
    One can manipulate the seeded-growth kinetics of block
    copolymer unimers to control the growth sequence of
    unimers and thus the comicelle morphology.
    Winnik group, Journal of the American Chemical Society, 2018
  3. Oncogene
    INHIBITING MYC BINDING TO THE E-BOX DNA
    MOTIF BY ME47 DECREASES
    TUMOUR XENOGRAFT GROWTH
    The Shin lab's designed protein ME47 decreased tumor growth in
    a triple negative breast cancer mouse model, a type of cancer with
    no effective treatments.
    Shin, Chan & Penn groups, Oncogene, 2017
  4. DNA
    PROTEIN DIMERIZATION PARTNERS ARE DICTATED
    BY THE DNA TARGET, NOT PROTEIN TARGET
    Many genes are regulated by protein hetero- or homodimers. Shin et
    al found that DNA bases outside the protein-DNA recognition target
    determine the protein dimerization partner.
    Shin Group, Molecular Biosystems, January 2017
  5. THE ROLE OF DIMER ASYMMETRY AND
    PROTOMER DYNAMICS IN ENZYME CATALYSIS
    Prosser and coauthor Pai examine a homodimeric enzyme, fluoroacetate
    dehalogenase, which converts a highly toxic pesticide into a harmless
    metabolite, and explore the role of enzyme dynamics in the process.
    Prosser Group, Science, January 2017

Awards:

Graham Garrett wins 2018 Chairís Doctoral Medal

Graham Garrett wins 2018 Chairís Doctoral Medal

Congratulations to Dr. Graham Garrett, the winner of the 2018 Chairís Doctoral Medal. Graham obtained his PhD in 2017 under the direction of Professor Mark Taylor.

In his thesis, Graham explores the area of physical organic chemistry and provides fundamental insights into previously unexplored types of molecular interactions and new modes of catalytic reactivity.


News and Announcements:

From basic science to better patient care

From basic science to better patient care

Nancy Khuu, 2nd year PhD student, is passionate about pathology. Through her research in Professor Eugenia Kumachevaís group, sheís exploring the chemistry of cancer biology. She hopes to eventually pursue medical education so she can translate her research into better care for patients.

We spoke to Nancy about her research and her studies in the department of chemistry.

 


Doug Stephan and Shana Kelley appointed as University Professors

Doug Stephan and Shana Kelley appointed as University Professors

Professors Doug Stephan and Shana Kelley have both been appointed as one of the five new University Professors announced this year. This is the highest academic rank at the University, recognizing exceptional scholarly achievement and preeminence in a particular field.

Professors Stephan and Kelley join 10 other University Professors with appointments or cross-appointments to the department of chemistry.

 


What will happen if we donít nurture the next generation of scientists?

What will happen if we donít nurture the next generation of scientists?

In a Globe and Mail op-ed, Professor Lewis Kay writes about educating future scientists in Canada.

"What is clear is that we must continue to nurture the next generation of scientists and those who are engaged in discovery-based work."

 

 


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