The material for this course is divided into six broad sections, as listed below. There are two weekly and one biweekly 1 hour lectures. Handouts will be available through the portal course site ahead of time, while lecture recordings will become available the following week. For more information and study tips, please consult the Lectures page. Students should read ahead in the course text, as well as use the assigned problems listed in the handouts to test their understanding of the course material.
Section | Subject | Week | Lab Set | |
---|---|---|---|---|
1 | What‘s in a Number? — introduction to measurement | 1 | no lab | |
1.1 | The nature and scope of analytical chemistry | |||
1.2 | Measurement terminology; errors in measurement | |||
1.3 | Error estimates; error distribution | 2 | A | |
1.4 | Significance test; calibration & resgression | |||
2 | How Pure is Pure? — standards and calibration | 3 | B | |
2.1 | Standards and reference materials | |||
2.2 | Determining purity – general methodologies | |||
2.3 | Volumetric analysis – titrations, complexometry, & gravimetry | 4 | ||
3 | All Charged Up! — electroanalytical chemistry | 5 | ||
3.1 | Electrochemistry review; Nernst equation | |||
3.2 | Potentiometry, reference electrodes | |||
3.3 | Membrane electrodes – pH and ISEs | 6 | ||
3.4 | Potentiometric titrations | |||
4 | Making Light Work — molecular spectroscopy | 7 | C & D | |
4.1 | Review of electromagnetic radiation | |||
4.2 | Electronic transitions in atoms and molecules | |||
4.3 | UV/visible spectrophotometry & Beer‘s Law | 8 | ||
4.4 | UV/visible instrumentation | |||
4.5 | molecular rovibrational transitions – IR | 9 | ||
4.6 | IR & FTIR instrumentation | |||
5 | A Bright Spark! — atomic emission and absorption | 10 | ||
5.1 | Atomic line spectra & spin multiplicity | |||
5.2 | Maxwell–Boltzmann equation in AS | |||
5.3 | Atom sources, sample introduction, flame processes | 11 | ||
5.4 | Flame atomic absorption & emission | |||
5.5 | Interference effects, calibration, standards addition | |||
6 | Degrees of Separation — introductory chromatography | 12 | ||
6.1 | Description & mechansim of separation | |||
6.2 | Definitions – retention & resolution | |||
6.3 | Gas & liquid chomaography instruments | |||
6.4 | Optimization, resolution, method selection |