A Tour of the cytochrome c oxidase

Please be patient while the structures in the left frame load. In order to display all of the structures in the tour properly, press 'View' buttons below in order (from 1 to the end).

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The structure of Na+-K+ pump was reported by Shinoda, T.; Ogawa, H.; Cornelius, F. and Toyoshima, C. in Nature 2009, 459, 446 (PDB IDs 2OCC for fully oxidized and 1OCR for fully reduced state).

Other useful sources:

Morth, J. P. et al. (2011). A Structural Overview of the Plasma Membrane Na+-K+-ATPase and H+-ATPase Ion Pumps. Nature Reviews, 12, 60-69. (A very useful current review.)

Morth, J. P. et al. (2007). Crystal Structure of the Sodium-Potassium Pump. Nature, 450, 1043-1050. (An earlier, lower resolution structure of pig renal Na-K pump; PDB ID 3B8E. The text is more informative and detailed than the one cited as a source for this tour.)

Palmgren, M. G., and Nissen, P. (2011). P-Type ATPases. Annu. Rev. Biophys., 40, 243-266. (An excellent current review addressing major P-type ATPases, including Na+-K+-ATPase.)

Tour Copyright: Robert Morris and Alen Hadzovic, 2012.