A Tour of Classical Zinc Finger


Please be patient while the structures in the left frame load. In order to display all of the structures in the tour properly, press 'View' buttons below in order (from 1 to the end).


Video 2. The surface potential of apoCaM.


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Figure 1. The EF hand motif for calcium ion binding (click on the thumbnail).

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Figure 2. The coordination environments of calcium cations in holoCaM (click on the thumbnails).



The NMR solution structure of apoCaM was reported by Kuboniwa, H., et al. in Nat. Struct. Biol. 1995, 2, 768-776; DOI: 10.1038/nsb0995-768 (PDB ID 1CFD).


Notes and references

[1] Berchtold, M.W., and A. Villalobo Biochim. Biophys. Acta 2014 1843, 398-435. (DOI: 10.1016/j.bbamcr.2013.10.021

[2] Haiech, J. et al. BBA Mol. Cell Res. 2019 1866, 1046-1053. (DOI: 10.1016/j.bbamcr.2019.01.014).


Copyright: Alen Hadzovic, 2023.

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The Guided Tours of Metalloproteins by Alen Hadzovic and Robert H. Morris is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License