We are interested in biomimetic polymer-based hydrogels that replicate in vivo ECM and can be used for 3D cell culture. We are developing hydrogels for cancer spheroid and skin spheroid growth and use them as in vitro models for high-throughput screening of drugs or fast optimization of multi-component formulations for skin care. We are combining this polymer-focused research with microfluidics. Currently, we explore the applications of these hydrogels for other cell populations.

We are interested in designing and synthesis of nanofibrillar biomimetic hydrogels that mimic the changes in structure, mechanical properties, and chemistry of fibrotic tissues. We use these fibrous hydrogels to support the 3D culture of cells relevant to fibrotic diseases. Our in vitro studies provide insight on changes occurring during of fibrosis of different tissues. We are alco interested in the role of stiffness and anisotropy of ECM on cell fate and cell response to therapeutic treatment.

We are designing materials for advanced wound dressings. Our research includes polymer synthesis and 3D printing of dressings that have antibacterial, anti-inflammation and would healing performance. One aspect of our work includes the design of wound dressings that withdraw, rather than release biologically active species much needed by bacteria. We are particularly interested in keloid scar formation.

We conduct research aimed at the use of biocompatible nature-derived nanoparticles in medicine. In one project, we explore the applications of phytoglycogen nanoparticles as lubricants for treatment of arthritis. In other project, we are interested in using lyposomes for the delivery of drugs and biologically active agents (e.g., vitamins) to multicellular spheroids.